Evidence supporting the use of: Corydalis
For the health condition: Insomnia
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Corydalis has a long history of use in traditional Chinese medicine (TCM), particularly for its sedative and analgesic properties. In TCM, the root of Corydalis yanhusuo is often used to "invigorate the blood" and "move qi," and is traditionally included in herbal formulas aimed at relieving pain and supporting relaxation or sleep. The use of Corydalis for insomnia is based on its calming effects, which practitioners believe may help quiet the mind and promote restful sleep.
Scientific evidence for Corydalis as a treatment for insomnia is limited and preliminary. Some animal studies and in vitro research have identified that certain alkaloids in Corydalis, such as tetrahydropalmatine (THP), may exert sedative and anxiolytic effects, possibly by modulating dopamine receptors or GABAergic activity in the central nervous system. However, clinical trials in humans are scarce, with only a handful of small studies suggesting potential benefits for sleep quality or latency. The methodological quality of these studies is generally low, and larger, well-controlled human trials are lacking.
In summary, Corydalis is primarily used to support or treat insomnia based on traditional practices, with a modest body of scientific evidence suggesting possible sedative effects. The overall quality and quantity of evidence supporting its use for insomnia remain limited.
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melatonin
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perilla
phytocannabinoids
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polygala root
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scrophularia root
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