Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Polygodial is a sesquiterpene dialdehyde found in certain plants such as Polygonum hydropiper (water pepper) and Tasmannia lanceolata (Tasmanian pepper). Its use as an insect repellent is supported by scientific studies demonstrating its deterrent and toxic effects against various insect species. Research shows that polygodial acts primarily as a feeding deterrent and contact repellent. Laboratory experiments have demonstrated its efficacy against pests such as aphids, mosquitoes, and termites. For example, studies published in journals like Pest Management Science and Journal of Agricultural and Food Chemistry document that polygodial disrupts feeding behavior and can cause avoidance or mortality in insects exposed to treated surfaces or extracts.

The mechanism of action appears to involve irritation and disruption of sensory processes in insects, possibly mediated by interaction with ion channels or by acting as an antifeedant. While polygodial has not been extensively commercialized in mainstream repellents, its insect-repellent properties are well-documented in the scientific literature, and it is sometimes cited as a lead compound for the development of botanical insecticides. However, the evidence is mostly from laboratory studies and not from large-scale field trials or widespread human use, so the evidence is rated as moderate (3/5).

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