Silk protein, particularly in the form of silk fibroin, has garnered scientific attention for its potential in supporting and treating injuries, especially within the field of tissue engineering and wound healing. Research has shown that silk fibroin possesses several properties beneficial for biomedical applications: it is biocompatible, has minimal immunogenicity, and can be processed into various formats such as films, sponges, and hydrogels. These characteristics make silk protein an attractive material for use as wound dressings and scaffolds for tissue regeneration.

Preclinical studies and some clinical investigations have indicated that silk-based materials can promote wound healing by providing a protective barrier, supporting cellular attachment and proliferation, and maintaining a moist environment conducive to tissue repair. For example, silk fibroin dressings have demonstrated efficacy in accelerating wound closure, reducing scar formation, and supporting the regeneration of skin and other tissues in animal models and limited human trials.

However, while positive results have been reported, most of the evidence comes from laboratory and early-stage clinical studies. Large-scale, high-quality randomized controlled trials in humans are still limited. Thus, while there is a scientific basis for the use of silk protein in injury treatment, further research is needed to fully establish its efficacy and best practices for clinical application.