Evidence supporting the use of: L-glutamine
For the health condition: Injuries

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

L-glutamine is a non-essential amino acid that plays a critical role in various metabolic processes, especially during stress and injury. The scientific rationale for using L-glutamine to support or treat injuries is based on its role in protein synthesis, immune function, and as a fuel source for rapidly dividing cells such as those in the gut and immune system. During injury or trauma, the body's demand for glutamine increases, sometimes exceeding the body's ability to produce it, leading to a condition described as "conditionally essential."

Clinical studies have evaluated L-glutamine supplementation primarily in the context of severe injuries such as burns, trauma, and post-surgical recovery. Some trials have shown that glutamine supplementation can reduce infection rates, preserve muscle mass, and improve immune function in critically ill or injured patients. For example, meta-analyses of randomized controlled trials suggest a modest benefit in reducing complications and length of hospital stay, particularly in surgical and trauma patients. However, the quality of the evidence is mixed, with some studies showing no significant benefit, and there remains controversy regarding optimal dosing and patient selection.

Overall, while there is scientific rationale and some clinical evidence supporting the use of L-glutamine in the context of injury (especially in critically ill patients), the strength of evidence is moderate at best, and it is not universally recommended for all types of injuries. More research is needed to clarify its role in broader injury recovery contexts.

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aloe vera
amino acids
bamboo
bayberry
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bromelain
chymotrypsin
collagen
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turmeric
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papain
protease
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silicon
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vitamin C
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vitamin E
zinc
chickweed
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hedychium spicatum
chaff flower
boxthorne
yarrow
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myrrh
solomon's seal
amber
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fungal enzymes blend (proprietary)
abies spectabilis
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