Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Connective tissue growth factor (CTGF), also known as CCN2, is a matricellular protein that plays a key role in tissue repair, wound healing, and fibrosis. The use of CTGF to support or treat injuries is primarily justified by scientific evidence, particularly from preclinical studies. CTGF is upregulated in response to tissue injury and is involved in processes such as cell proliferation, migration, angiogenesis, and extracellular matrix production. Animal models have demonstrated that CTGF can promote the repair of tendons, skin, and other connective tissues by enhancing collagen synthesis and tissue remodeling. For example, studies have shown that exogenous administration of CTGF or gene therapy approaches targeting CTGF can accelerate wound healing and improve the organization of repaired tissue in models of tendon and skin injury (Leask, 2010). However, overexpression of CTGF is also associated with pathological fibrosis, indicating that its use must be precisely regulated (Wang et al., 2015). Human clinical data on CTGF-based therapies are still limited, and most current applications remain experimental. In summary, while there is a scientific rationale and supportive preclinical evidence for the use of CTGF in treating injuries, robust clinical trials are lacking, and its therapeutic application is not yet standard practice.

More about Connective tissue growth factor
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Other ingredients used for Injuries

aloe vera
amino acids
bamboo
bayberry
beeswax
Indian frankincense
bovine
bromelain
chymotrypsin
collagen
Coptis chinensis
turmeric
dandelion
dog rose
dyer’s woad root
endo-peptidase
exo-peptidase
fungal protease
ginger
l-alanyl-l-glutamine
l-glutamine
l-proline
licorice root
spruce
ornithine alpha-ketoglutarate
papain
protease
protein
purified silver
reishi mushroom
serratiopeptidase
silicon
trypsin
vitamin C
vitamin D
vitamin E
zinc
chickweed
typhonium
clerodendrum indicum
hedychium spicatum
chaff flower
boxthorne
yarrow
moss
myrrh
solomon's seal
amber
sheep's sorrel
wintergreen
fungal enzymes blend (proprietary)
abies spectabilis
geranium
arnica
Aralia
Avens
Asclepias cordifolia
akebia
Animal Tissue
Antler
Aquilegia viridiflora
Asiaticoside
Ardisia
Agave
Agrimony
Achyranthes
Anamu
Abrus
Albizia
Aconite
Ajuga
Aucubin
Anserina
Albumin
American Liverleaf
Aquilegia formosa
Asam gelugor
Allantoin
Ampelopsis
Agonandra
Agrimonia pilosa
Acemannan
Acetylsalicylic acid
Abuta
Alkanna
Alstonia macrophylla
Amor seco
Arani
Animal protein
Bee Propolis
Biopeptide
Bai Ji
Baliospermum
Black spruce
Blackthorn
Bulnesia sarmientoi
Blubber oil
Blepharis
Black-Eyed Susan
Boswellic Acid
Beef Protein
Barleria
Bone Marrow
Bovine Protein
Benzoin
Begonia fimbristipula
Bindweed
Banyan
Bletilla
Black root
Comfrey
Centella triterpenes
Calendula
Casearia esculenta
Common Monkey Flower
Calotropis gigantea
Clerodendrum trichotomum
Cinquefoil
Cyathula
Ceylon Leadwort
Cedar
Campylandra fimbriata
Centipeda
cypress
Cranesbill
Chinese Thoroughwax
Carlina
Carrapichinho
Cedrus libani
Ceanothus integerrimus
Connective tissue growth factor
Cocklebur
Collinsonia
Castor Oil
Calyptridium umbellatum
Casearia sylvestris
Didymocarpus
Deer Root
Damulin A
Deer Velvet
Dragon's Blood
Devil's Club
Dianthrone
Dwarf Nettle
Dimethyl sulfoxide (DMSO)
Davilla rugosa
Deerbrush
Epidermal Growth Factor
Erythropalum scandens
Erigeron
Elephant Vine
Erodium cicutarium
Evodia
Elk antler
Echinacea
Emu Oil
Euphorbia
Egg protein
Elastase
Fiesta Flower
Flueggea suffruticosa
Fang-Feng
Formosan Sweet-Gum
Ficin
Fibrinase
Frankincense
Fireweed
Four leaved grass
Genipap
Gleditsia
Glutamine
Gambir
Genipa americana
Golden Eye-grass
Giant Blazingstar
Giant Trillium
Golden Ragwort
Golden Shower Tree
Golden Willow
Guazuma ulmifolia
Oak
Snakeroot (unspecified)
Silk protein

Other health conditions supported by Connective tissue growth factor

Cartilage Damage
Injuries
Scars / Scar Tissue
Surgery (healing from)
Wounds and Sores

Products containing Connective tissue growth factor

We currently have no products on Caring Sunshine that contain this ingredient.