Aloe vera has a long history of use for treating skin injuries, particularly burns, wounds, and minor cuts. This traditional application has been supported by a substantial body of scientific research. Various clinical studies have demonstrated that topical application of Aloe vera gel can accelerate wound healing, reduce inflammation, and improve skin hydration. For example, randomized controlled trials have shown that Aloe vera gel can promote faster healing of first- and second-degree burns compared to standard treatments or placebos. The active compounds in Aloe vera, such as polysaccharides (notably acemannan), glycoproteins, and antioxidants, are thought to contribute to these effects by stimulating fibroblast activity, enhancing collagen synthesis, and exerting anti-inflammatory and antimicrobial actions.

Systematic reviews and meta-analyses generally support the efficacy of Aloe vera for minor skin injuries, though results can be inconsistent depending on the formulation and extent of injury. While Aloe vera is widely considered safe for topical use, some individuals may experience allergic reactions. The evidence is strongest for superficial injuries; however, for deep wounds or chronic ulcers, the results are less clear and more research is needed. Overall, the use of Aloe vera for supporting the healing of minor injuries is justified by both tradition and a moderate-to-strong scientific foundation.