Evidence supporting the use of: Immunoglobulins
For the health condition: Influenza

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Immunoglobulins (also called antibodies) have been investigated and used as a therapeutic option for influenza, especially in severe cases or when other treatments are unavailable or ineffective. The use of convalescent plasma or hyperimmune globulin, which contains high titers of influenza-specific antibodies, has a historical precedent dating back to the 1918 influenza pandemic, where some observational studies suggested reduced mortality in recipients. More recently, several clinical studies and meta-analyses have assessed the efficacy of immunoglobulin therapy (either standard intravenous immunoglobulin [IVIG] or specific hyperimmune globulin) in treating severe influenza, particularly in hospitalized or immunocompromised patients.

The evidence is mixed. Some small randomized controlled trials and observational studies have suggested a possible reduction in viral load or improvement in clinical outcomes, but others have failed to show significant benefit. The 2018 Infectious Diseases Society of America (IDSA) guidelines acknowledge that data are insufficient to recommend routine use of immunoglobulin products for influenza, but they may be considered in certain severe or refractory cases. The overall quality of evidence is moderate (hence a rating of 3), with ongoing research needed to clarify which patients may benefit most. Immunoglobulins are not standard therapy for uncomplicated influenza, but their use in severe cases is supported by a moderate level of scientific evidence, particularly in the context of limited antiviral options.

More about Immunoglobulins
More about Influenza

Other ingredients used for Influenza

green chiretta
astragalus
Myrobalan
benegut perilla (proprietary)
black garlic
black pepper
Indian frankincense
bupleurum falcatum
camu camu
catechins
caterpillar mushroom
chaga mushroom
Coptis chinensis
cordyceps
turmeric
dog rose
echinacea purpurea
elderberry
ginger
glehnia root
goldenseal
gooseberry
Greek mountain tea
green tea
honeysuckle
L-cysteine
Lactobacillus casei
Lactoferrin
Lactoperoxidase
Lentinula edodes mycelia
licorice root
Monolaurin
Nettle
quercetin
reishi mushroom
selenium
spirulina
sweet wormwood
vitamin C
vitamin D
zhejiang fritillary
Zinc
boneset
tangerine
alpinia galangal
Myrrh
Yerba santa
chrysanthemum
flowering quince
ganoderma
anemarrhena asphodeloides
eucalyptus
Abies spectabilis
Algae
avens
Agarikon Mushroom
apple cider vinegar
Agastache
Anamarrhena
Acacia
Agrimony
Allicin
anamu
AHCC
andrographolide
American Liverleaf
astragaloside
Andrographis
Alstonia scholaris
Adenophora
Alliin
Asarum sieboldii
bee propolis
black seed
Baikal Skullcap
Bryonia
balsam
Basidiomycota
borage
Bupleurum
baicalin
Black Hellebore
balloon flower
Clerodendrum trichotomum
coconut oil
coriolus mushroom
Clerodendrum phlomidis
carvacrol
cineole
Centipeda
Cistus
Chaenomeles lagenaria
currant
Chondrus
Ephedra
European Elder
elk antler
Echinacea
Elder
Euphorbia
Embelia
fat liver oil
flavanones
frankincense
flavones
Glehnia littoralis
Guaco
Gallesia
Glycyrrhizin
Hyperoside
Houttuynia
honey loquat syrup
Immunoglobulin G
iridoids
Lycium
Ledebouriella
Lomatium
lichen
Lycopodium
labrador tea
little ironweed
liverwort
Meadow sage
Microtea debilis
Neoandrographolides
Onosma bracteatum
Osthole
Premna
Platycodon
Pelargonium
Pentatropis capensis
Polygonatum
Polygonum
ravinsara
Sweet Annie
Salvia
Sambucus nigra
Sulfated polysaccharide
Shikimic Acid
Sweet Bay
Sundew
Tremella
Umckaloabo
Visnea Mocanera
Vasicine
Xanthophyll
Zingerone

Products containing Immunoglobulins

We currently have no products on Caring Sunshine that contain this ingredient.