Evidence supporting the use of: Goldenseal
For the health condition: Influenza

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Goldenseal (Hydrastis canadensis) has a long history of use in traditional herbal medicine, primarily among Native American tribes and early North American settlers. Traditionally, goldenseal was used to treat a range of infections and inflammatory conditions, including respiratory tract infections such as colds and flu (influenza). The herbal remedy is prized for its antimicrobial, anti-inflammatory, and immune-modulating properties, largely attributed to its active alkaloid constituents, such as berberine, hydrastine, and canadine.

Despite its traditional use, there is limited scientific evidence specifically supporting goldenseal’s effectiveness against influenza viruses. Most studies have focused on the general antimicrobial and immunostimulatory activities of berberine and related compounds. While some laboratory studies demonstrate that berberine can inhibit the replication of certain viruses or modulate immune responses, direct clinical evidence for goldenseal’s benefit in treating or preventing influenza in humans is lacking. Systematic reviews and authoritative health organizations generally do not recognize goldenseal as an evidence-based treatment for influenza.

In summary, while goldenseal is traditionally used to support respiratory health and combat infections, scientific validation of its effectiveness for influenza is minimal. Users should exercise caution and consult healthcare professionals before using goldenseal, especially due to potential side effects and interactions with medications.

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