Evidence supporting the use of: Epigallo catechin
For the health condition: Influenza

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Epigallocatechin gallate (EGCG), a major catechin found in green tea, has attracted scientific interest for its potential antiviral properties, including activity against influenza viruses. Several in vitro studies have demonstrated that EGCG can inhibit influenza virus replication by interfering with key stages of the viral life cycle, such as virus adsorption, entry into host cells, and viral RNA synthesis. For example, research published in peer-reviewed journals (e.g., Antiviral Research, 2011; Journal of Antimicrobial Chemotherapy, 2012) has shown that EGCG can inactivate viral particles and reduce infectivity in cell culture models.

However, evidence from human clinical trials remains limited. While some animal studies suggest potential benefits, robust, well-controlled clinical trials in humans are lacking. Thus, although the mechanistic and preclinical evidence is promising, there is insufficient direct clinical evidence to support the use of EGCG as a standalone treatment or preventive agent for influenza in humans. It is not an approved antiviral drug, and its efficacy in real-world settings has not been established. Therefore, while the use of EGCG for influenza is supported by some scientific investigation, the overall evidence is preliminary and rates a 2 on a 0-5 scale.

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