Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Vitamin B12 (Hydroxycobalamin) is used in the management of Inflammatory Bowel Disorders (IBD), such as Crohn's disease and ulcerative colitis, due to well-established scientific evidence. IBD, particularly Crohn’s disease, often involves the terminal ileum, which is the site of vitamin B12 absorption. Inflammation, surgical resection, or other dysfunctions of the ileum can lead to malabsorption and subsequent B12 deficiency. This deficiency can cause megaloblastic anemia, neurological symptoms, and other systemic issues if untreated.

Several clinical guidelines recommend routine monitoring of B12 levels in patients with IBD, especially those with ileal involvement or resection. Numerous studies have documented a higher prevalence of B12 deficiency in these populations. Supplementation with hydroxycobalamin (or other forms of B12) is considered standard of care in confirmed deficiency cases, and is supported by clinical practice guidelines from gastroenterological societies.

However, it is important to note that B12 supplementation is not a treatment for IBD itself, but rather for the deficiency that commonly arises as a complication. There is little evidence to suggest that B12 directly impacts IBD disease activity, inflammation, or remission rates. Its use is therefore justified and validated scientifically, but with a specific indication: correction of deficiency, not primary disease management.

More about Vitamin B12 (Hydroxycobalamin)
More about Inflammatory Bowel Disorders

Other ingredients used for Inflammatory Bowel Disorders

Other health conditions supported by Vitamin B12 (Hydroxycobalamin)

Products containing Vitamin B12 (Hydroxycobalamin)