Evidence supporting the use of: Procyanidin (unspecified)
For the health condition: Inflammatory Bowel Disorders

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Procyanidins, a class of polyphenolic compounds abundant in foods like grapes, apples, and cocoa, have been investigated for their anti-inflammatory and antioxidant properties. There is emerging scientific interest in the potential of procyanidins to support or treat Inflammatory Bowel Disorders (IBD) such as Crohn’s disease and ulcerative colitis. Preclinical studies, primarily in animal models and cell cultures, suggest that procyanidins may help reduce intestinal inflammation by modulating inflammatory cytokine production, inhibiting NF-κB signaling, and protecting intestinal barrier function. For example, studies in mice have shown that procyanidin-rich extracts can attenuate colitis induced by chemicals like dextran sulfate sodium (DSS), with observed reductions in inflammatory markers and improvement in histological parameters.

However, evidence in humans is limited. There are very few clinical trials, and those that exist are small and preliminary. The majority of the data comes from animal or in vitro studies, which do not always translate to human efficacy. While the mechanistic rationale is plausible and preclinical results are promising, there is insufficient high-quality clinical evidence to support routine use of procyanidins for IBD. Thus, the scientific support is currently weak to moderate (rated 2/5), and procyanidins should not be considered a validated or primary therapy for IBD outside of research settings.

More about Procyanidin (unspecified)
More about Inflammatory Bowel Disorders

Other ingredients used for Inflammatory Bowel Disorders

2'-Fucosyllactose
akkermansia muciniphila
algal oil
aloe vera
alpha-glycosyl isoquercitrin
alpha-linolenic acid (ALA)
anthocyanins
bacillus clausii
bacillus subtilis
barberry
barley
beta caryophyllene
bifidobacterium bifidum
bifidobacterium breve
bifidobacterium infantis
bifidobacterium lactis
bifidobacterium longum
butyrate triglyceride
cat's claw
chamomile
citrus pectin
Coptis chinensis
turmeric
curcumin
dandelion
DHA (docosahexaeonic acid)
EPA (eicosapentaenoic acid)
fish oil
flaxseed
fructooligosaccharides (FOS)
inulin
isomalto-oligosaccharide
l-glutamine
lactobacillus brevis
lactobacillus casei
lactobacillus crispatus
lactobacillus fermentum
lactobacillus gasseri
lactobacillus lactis
lactobacillus paracasei
lactiplantibacillus plantarum
lactobacillus reuteri
lactobacillus rhamnosus
lactobacillus salivarius
lactococcus lactis
licorice root
luteolin
marshmallow
n-acetyl-glucosamine
n-acetyl-cysteine (NAC)
nicotinamide riboside
omega-3 fatty acids
pectin
peppermint oil
butyric acid
psyllium
reishi mushroom
saccharomyces boulardii
shiitake mushroom
slippery elm bark
specialized pro-resolving mediators (SPMs)
spirulina
streptococcus thermophilus
tributyrin
Urolithin A
vitamin C
vitamin D
vitamin D3
xylanase
xylooligosaccharides
zinc
bentonite
punarnava
rubia cordifolia
swertia
myrrh
algae
7,14-Hydroxy-Docosapentaenoic Acid
Apigenin
Andrographolide
Avocado
anthocyanidins
Acemannan
Arabinoxylan
Apocynin
Arctiin
Astragalin
Bifidobacterium
Bifidobacterium adolescentis
Brassica
Boswellic Acid
Butternut
Basidiomycota
Boswellia
Bacillus licheniformis
Bioflavonoids
Bifidobacterium animalis
Bacteria
Bifidobacteria
Bacillus
Cichoric acid
Cruciferous
Casticin
Celandine
Chirata
Cannabidiol
Enterococcus
Eicosapentaenoic Acid
Ellagitannin
Fucoidan
Fiber
Frangula
Flavans
Glycomacropeptides
Glycosphingolipids
Glutathione
Galactooligosaccharides
Glycyrrhetinic Acid
Glucosinolates

Products containing Procyanidin (unspecified)

We currently have no products on Caring Sunshine that contain this ingredient.