Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Bifidobacterium infantis is a probiotic bacterium that has been increasingly studied for its role in supporting gut health, particularly in individuals with Inflammatory Bowel Disorders (IBD) such as Crohn’s disease and ulcerative colitis. The scientific rationale for its use centers around its ability to modulate the gut microbiome, enhance the intestinal barrier, and reduce inflammation. Several clinical studies and randomized controlled trials have investigated its effects on IBD patients. For example, a landmark study published in the American Journal of Gastroenterology (2005) found that supplementation with B. infantis 35624 led to significant improvement in symptoms and markers of inflammation in patients with irritable bowel syndrome, and later studies extended these findings to IBD populations.

Meta-analyses and systematic reviews suggest that certain Bifidobacterium strains, including B. infantis, can reduce pro-inflammatory cytokines (such as TNF-α and IL-6) and improve subjective well-being in some patients. However, the evidence is not uniformly strong across all IBD patient groups, and not all studies have shown significant clinical benefit. The strain-specific effects, small sample sizes, and variability in study designs have limited the strength of recommendations. Nonetheless, the underlying biological plausibility and positive findings in several controlled studies provide a scientific basis for its use as an adjunctive therapy, rather than a primary treatment, for IBD.

More about Bifidobacterium infantis
More about Inflammatory Bowel Disorders

Other ingredients used for Inflammatory Bowel Disorders

Other health conditions supported by Bifidobacterium infantis

Products containing Bifidobacterium infantis

Nature's Sunshine Eleven Elevated (NutriBiome)
Nature's Sunshine Probiotic Eleven
Nature's Sunshine Sunshine Heroes Probiotic Power