Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Thiosulfinates are sulfur-containing compounds primarily found in garlic (Allium sativum), with allicin being the most well-known example. The use of garlic and its extracts for the treatment and prevention of infections has deep roots in traditional medicine, but modern research has provided some scientific validation, particularly regarding antibacterial and antifungal effects.

Regarding viral infections, there is limited but growing scientific evidence suggesting that thiosulfinates possess antiviral activity [source]. In vitro studies have demonstrated that allicin and other thiosulfinates can inhibit the replication of certain viruses, such as influenza virus and herpes simplex virus. Proposed mechanisms include interference with viral envelope proteins and inhibition of viral entry or replication. However, the majority of these findings are restricted to cell cultures and animal models, and robust clinical trials in humans are lacking.

While some small-scale human studies and anecdotal evidence suggest potential benefits—such as reduced severity or duration of common cold symptoms—these results are not conclusive. Systematic reviews and meta-analyses indicate that evidence for antiviral efficacy in humans remains weak and further research is needed to clarify the role of thiosulfinates in viral infection management.

In summary, while there is some scientific basis for the antiviral use of thiosulfinates, especially in laboratory settings, the current level of evidence supporting their clinical use for viral infections is limited.

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