Chinese Tinospora (Tinospora sinensis), also sometimes referred to as "Chinese Guduchi," has a longstanding use in traditional Chinese medicine (TCM) and other Asian traditional systems for the management of infections, including those believed to be viral in nature. Traditional texts and pharmacopeias describe its use for "clearing heat and toxins," which in TCM theory often corresponds to infectious diseases and febrile illnesses. The use of Tinospora species is more documented in Indian Ayurveda (as Guduchi, Tinospora cordifolia), but Tinospora sinensis has been similarly employed in folk practice in China for fever, malaise, and various infectious conditions.

However, modern scientific studies specifically on Tinospora sinensis are limited, and most available research focuses on related species or in vitro antioxidant/immune-modulating effects rather than direct antiviral activity in humans. There are some preclinical studies suggesting immunomodulatory and anti-inflammatory properties, yet robust clinical data are lacking. Thus, its use for viral infections is primarily justified by tradition, not strong scientific validation. Evidence level is rated as 2, reflecting traditional use with minimal supporting scientific evidence.