Evidence supporting the use of: Arabinogalactan
For the health condition: Infection (viral)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Arabinogalactan, a polysaccharide derived primarily from the larch tree (Larix species), has a modest but growing evidence base for its use in supporting the immune system, particularly in the context of viral infections. Several small clinical studies and laboratory investigations suggest that arabinogalactan may enhance immune function by modulating the activity of natural killer (NK) cells and macrophages, and by increasing the production of cytokines involved in the body's defense against viral pathogens.

One randomized, double-blind, placebo-controlled trial found that supplementation with larch arabinogalactan reduced the incidence of common cold episodes in healthy adults, suggesting a possible protective effect against upper respiratory viral infections. In vitro studies also indicate that arabinogalactan can stimulate immune cells and promote the growth of beneficial gut bacteria, which may indirectly support antiviral defenses.

However, the clinical evidence remains limited in size and scope. Most studies report mild improvements in immune markers or slight reductions in infection frequency, rather than robust antiviral activity. No major regulatory agencies currently endorse arabinogalactan as a treatment for viral infections, and more large-scale, high-quality human trials are needed to confirm its efficacy. Nonetheless, the existing scientific literature provides some justification for its use as an immune-supportive supplement, particularly for those seeking to reduce the risk or severity of common viral illnesses.

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