Evidence supporting the use of: Alliin
For the health condition: Infection (viral)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Alliin is a sulfur-containing compound found in garlic (Allium sativum) and is the precursor to allicin, which forms when garlic is crushed or chopped. The use of garlic for infections, including viral infections, has a long history in traditional medicine. However, alliin itself has been studied for its antimicrobial properties, including antiviral effects. In laboratory (in vitro) studies, garlic extracts containing alliin and related compounds have shown some activity against various viruses, such as influenza, herpes simplex virus, and others. The exact mechanism is thought to involve interference with viral replication and modulation of immune responses.

However, strong clinical evidence in humans specifically for alliin against viral infections is limited. Most clinical studies have focused on garlic extracts as a whole, rather than isolated alliin. Some small trials suggest that garlic supplementation may reduce the incidence or severity of viral respiratory infections, but these studies often do not isolate alliin as the active component. Overall, while there is scientific interest and some preliminary in vitro and animal data, the direct evidence for alliin as a treatment or preventive agent for viral infections in humans is weak. Thus, the current scientific evidence supporting alliin’s use for viral infections is modest and warrants further research.

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