Evidence supporting the use of: Ajoene
For the health condition: Infection (viral)

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Ajoene is a sulfur-containing compound derived from garlic (Allium sativum), and it has attracted scientific interest for its potential antiviral properties. Several in vitro studies have demonstrated that ajoene can inhibit the replication of various viruses, including HIV-1, influenza virus, and herpes simplex virus. The proposed mechanisms include interference with viral entry into host cells, inhibition of viral proteases, and modulation of host immune responses. For example, a study published in Antiviral Research (1987) showed ajoene's ability to inhibit HIV-1 replication in cultured cells. Additionally, research indicates that ajoene may alter membrane fluidity and block viral fusion processes. Despite these promising findings, most evidence supporting ajoene's antiviral effects comes from laboratory (in vitro) experiments, and there is a lack of robust human clinical trials confirming its efficacy for treating viral infections. Its use in traditional medicine has been more focused on garlic as a whole rather than isolated ajoene, with garlic being used for general immune support and to combat infections. Therefore, while there is some scientific basis for considering ajoene in the context of viral infections, the evidence is currently limited to preclinical studies. Further research, especially well-designed clinical trials, is needed to determine its safety, efficacy, and optimal dosing in humans for viral infection treatment or prevention.

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Agastache
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AHCC
Ajoene
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Alkylglycerols
Alliin
Allium tuberosum
alpha-pinene
Alstonia scholaris
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apple cider vinegar
arabinogalactan
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Baccharis dracunculifolia
baicalin
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barberry
Bauhinia
bee propolis
Belamcanda
berberine
beta-glucan
betel
betulinic acid
black cumin
Blepharis
boneset
Brazilian peppertree
burdock
calamus
Campsiandra angustifolia
carvacrol
cassia bark
casticin
cat's claw
Centipeda
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Coptis chinensis
coriolus mushroom
curcumin
cuspidatum root
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diallyl disulfide (DADS)
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elderberry
eucalyptus
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fernbush
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fucoidan
galangin
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geranium
ginger
Globulins
Glucan peptides
golden shower tree
goldenseal
Graviola
honeysuckle
Houttuynia
Humic acid
Hypericin
immunoglobin G
Immunoglobulin G
iodine
Ivy
Java brucea
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knotgrass
Labdanum
Lactobacillus paracasei
Lactococcus rhamnosus
Lactoferrin
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lauric acid
Lentinan
lichen
licorice root
liverwort
Lomatium
mangosteen
mangostin
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Matapalo Tree
Microtea debilis
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Monolaurin
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oriental arborvitae
pau d'arco
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pistacia integerrima gall
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ravinsara
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selenium
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spirulina
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