Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Plectranthus amboinicus, also known as Indian borage or Cuban oregano, has been used traditionally in various cultures to treat respiratory and skin infections. Scientific studies have explored its antimicrobial properties, mainly in vitro (test tube) settings. Research indicates that extracts of P. amboinicus—particularly essential oils rich in compounds like carvacrol and thymol—exhibit antibacterial activity against some common bacterial pathogens, such as Staphylococcus aureus, Escherichia coli, and Pseudomonas aeruginosa. For example, studies published in journals such as the Journal of Ethnopharmacology and Asian Pacific Journal of Tropical Biomedicine have reported moderate antibacterial effects, especially against Gram-positive bacteria.

However, most evidence comes from laboratory experiments rather than clinical trials in humans. There is a lack of robust clinical research to confirm the efficacy and safety of P. amboinicus for treating bacterial infections in real-world settings. Therefore, while scientific validation exists at a preliminary level (in vitro), there is insufficient high-quality clinical evidence to fully endorse its use for infection treatment. The evidence rating of 2 reflects promising laboratory results but limited real-world or clinical validation.

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