Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Lactobacillus brevis is a probiotic bacterium that has been investigated for its potential role in supporting or treating bacterial infections, primarily by enhancing the host's natural defenses rather than directly eradicating pathogens. The scientific evidence supporting its use is limited but emerging, mainly from in vitro (laboratory) studies, some animal research, and a few small-scale human investigations. L. brevis has been shown to produce antimicrobial substances (such as bacteriocins and organic acids) that can inhibit the growth of certain pathogenic bacteria, including Escherichia coli and Staphylococcus aureus. Additionally, it may competitively exclude harmful microbes by colonizing mucosal surfaces and modulating the immune response, enhancing the production of protective cytokines and antibodies.

Despite these promising mechanisms, high-quality clinical trials in humans are scarce, and most available studies focus on mixed probiotic formulations rather than L. brevis alone. The evidence is somewhat stronger for its use in managing or preventing infections of the gastrointestinal tract (such as antibiotic-associated diarrhea), but not for systemic or severe bacterial infections. Thus, while there is a scientific basis for its potential benefit, evidence for its efficacy as a primary or sole treatment for bacterial infections remains limited, and it is not recommended as a substitute for conventional antibiotics. Further well-designed clinical trials are needed to clarify its specific role in infection management.

More about lactobacillus brevis
More about Infection (bacterial)

Other ingredients used for Infection (bacterial)

Other health conditions supported by lactobacillus brevis

Products containing lactobacillus brevis

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