Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Desmodium molliculum, commonly known as "manayupa" in South America, has a long history of use in traditional medicine, particularly in Peru and other Andean regions. Traditionally, it has been used to treat a variety of ailments, including infections and inflammation. Folk healers commonly prepare infusions or decoctions from its aerial parts to address bacterial infections, particularly those affecting the urinary tract, wounds, and skin conditions. While modern scientific studies directly evaluating its antibacterial activity are limited, there is some preliminary research indicating that extracts of Desmodium molliculum possess moderate antibacterial properties in vitro against certain bacterial strains. However, these studies are not comprehensive and do not provide strong clinical evidence. The traditional use is well-documented in ethnobotanical surveys, where local populations consistently report its application for infection-related symptoms. Despite this, the evidence supporting its effectiveness is primarily anecdotal and based on historical use rather than rigorous clinical trial data. Therefore, the justification for its use in treating bacterial infections is rooted in tradition, with only modest scientific support from laboratory studies and no robust clinical validation to date.

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