Evidence supporting the use of: Prickly ash
For the health condition: Infection

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Synopsis

Source of validity: Traditional
Rating (out of 5): 1

Prickly ash (Zanthoxylum americanum, also called Northern prickly ash) has been traditionally used in various North American indigenous and folk medicine systems to support or treat infections, particularly for its purported antimicrobial and immune-boosting properties. Historical records indicate that Native American tribes used the bark and berries of prickly ash to address issues such as sore throats, fevers, toothaches, and other symptoms frequently associated with infections. The plant contains compounds like alkaloids, lignans, and essential oils, which may contribute to its antimicrobial activity in vitro. However, the evidence supporting its efficacy for treating infections in humans is primarily anecdotal and rooted in tradition. There are very few clinical studies, and most of the available scientific research is limited to laboratory experiments showing some antibacterial or antifungal effects in test tubes, not in living organisms. Thus, while prickly ash has a long-standing historical use for infections, there is insufficient scientific validation to support its clinical effectiveness for this purpose. People considering its use should consult healthcare professionals, as more research is needed to determine its safety and efficacy in treating infections.

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