Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Citrus maxima, commonly known as pomelo, has a long history of use in traditional medicine across Southeast Asia and other tropical regions. Traditional practitioners have used various parts of the plant, including the fruit, peel, and leaves, to address a range of ailments, including infections. Ethnobotanical records indicate its application for treating coughs, colds, and wounds, suggesting an empirical belief in its antimicrobial or immune-supporting properties.

Scientific studies on Citrus maxima regarding infection are limited but do provide some support for its traditional use. In vitro experiments have demonstrated that extracts from the fruit peel and leaves possess antimicrobial activity against certain bacteria and fungi. For example, studies have shown effectiveness against Staphylococcus aureus, Escherichia coli, and Candida albicans, attributed in part to the presence of flavonoids, essential oils, and other phytochemicals. However, most of this research is preclinical, and there is a lack of robust clinical trials in humans to confirm efficacy and safety for treating infections.

In summary, the use of Citrus maxima for infections is primarily supported by traditional practices, with some preliminary scientific evidence from laboratory studies. The overall strength of evidence remains modest due to the absence of high-quality clinical data.

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