Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Eurycoma longifolia, commonly known as Tongkat Ali, has been traditionally used in Southeast Asian herbal medicine, primarily to enhance male vitality, libido, and overall energy. The traditional uses are often associated with improving hormonal balance, especially testosterone, which is regulated in part by the hypothalamic-pituitary-gonadal (HPG) axis. While there is historical precedent for its use in supporting hormonal health, direct traditional references to the hypothalamus as a target are sparse, as indigenous systems typically do not specify Western anatomical structures.

Scientific studies have explored Eurycoma longifolia's effects on testosterone levels and sexual function, with some evidence of mild increases in testosterone in men with low baseline levels. However, these studies usually measure downstream hormonal outcomes rather than direct effects on hypothalamic function. There is limited preclinical evidence suggesting that Eurycoma longifolia may modulate the HPG axis, but robust human data specifically linking its use to hypothalamic health or function are lacking.

In summary, while Eurycoma longifolia is traditionally used for purposes that indirectly involve the hypothalamic axis (such as hormonal balance and vitality), there is insufficient direct scientific evidence to validate its targeted use in supporting the hypothalamus itself. Its application for hypothalamic support is thus justified primarily by traditional use and not by strong scientific validation.

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