Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Rutin is a flavonoid commonly found in various fruits and vegetables, such as buckwheat, apples, and citrus fruits. Its use for supporting or treating hypertension has some scientific basis, though the strength of clinical evidence is limited. Preclinical studies, particularly in animal models, suggest that rutin may help lower blood pressure. Proposed mechanisms include its antioxidant effects, improvement of endothelial function, and modulation of nitric oxide production, which can lead to vasodilation. For example, a 2013 study in rats demonstrated that rutin supplementation was associated with reduced systolic blood pressure, likely due to its ability to decrease oxidative stress and enhance vascular relaxation.

However, human clinical trials are scarce. A few small-scale studies have reported modest improvements in blood pressure among individuals with hypertension or metabolic syndrome, but these results are not yet robust or widely replicated. The lack of large, well-controlled trials means that the evidence base for rutin’s antihypertensive effects in humans remains weak. Nevertheless, rutin is sometimes included in dietary supplements targeting cardiovascular health, based on its biochemical properties and promising preliminary data.

In summary, while there is some scientific rationale and early evidence suggesting rutin may support blood pressure regulation, the current level of evidence is insufficient to recommend it as a primary treatment for hypertension. More rigorous human studies are needed to confirm its efficacy and safety for this indication.

More about rutin
More about Hypertension

Other ingredients used for Hypertension

Other health conditions supported by rutin

Products containing rutin

Nature's Sunshine Mega-Chel
Nature's Sunshine MultiVitamin & Mineral (Time Release)
Nature's Sunshine Super Supplemental
Nature's Sunshine Super Supplemental (Without Iron)
Nature's Sunshine Super Trio
Nature's Sunshine Vari-Gone
Nature's Sunshine B-Complex
Nature's Sunshine Vitamin C (1000 mg, Time Release)
Nature's Sunshine Vitamin C (1000 mg, Time Release)
Nature's Sunshine Vitamin C Ascorbates
Nature's Sunshine Citrus Bioflavonoids (Vitamin C)