Synopsis

Source of validity: Scientific
Rating (out of 5): 1

Vitamin C (ascorbic acid) has been explored as an adjunctive therapy for viral hepatitis, but the supporting evidence is weak and largely limited to preliminary studies and theoretical rationale. Some early research from the mid-20th century suggested potential benefits of high-dose intravenous vitamin C in acute viral hepatitis, hypothesizing that its antioxidant properties might reduce liver inflammation and promote recovery. However, these studies were typically small, uncontrolled, and lacked rigorous methodology. More recent research has focused on vitamin C’s general role in immune function and its antioxidant effects, which could be relevant given the oxidative stress associated with hepatitis. Nonetheless, there is little high-quality clinical evidence demonstrating that vitamin C supplementation significantly alters the course or outcome of hepatitis A, B, or C infections. Major guidelines from organizations such as the World Health Organization or the American Association for the Study of Liver Diseases do not recommend vitamin C as a standard therapy for hepatitis. In summary, while there is a scientific rationale and some limited early research, the evidence base remains weak, and vitamin C should not be considered a primary or sole treatment for hepatitis.

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