Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Protein intake is an important consideration in the management of hepatitis, particularly chronic liver diseases such as hepatitis B and C. Hepatitis, characterized by inflammation of the liver, often leads to increased protein catabolism and muscle wasting (sarcopenia). Scientific literature supports the use of adequate dietary protein to help maintain or restore muscle mass, support immune function, and facilitate hepatic regeneration. Unlike earlier beliefs that high protein intake could precipitate hepatic encephalopathy in liver disease, more recent evidence suggests that moderate to high protein diets do not worsen encephalopathy in most patients and are in fact beneficial.

Clinical guidelines now recommend that patients with chronic hepatitis maintain a normal or slightly increased protein intake (about 1.0–1.5 g/kg per day), unless severe hepatic encephalopathy is present. This is based on studies showing that adequate protein supports the repair of hepatocytes, helps prevent malnutrition, and improves overall outcomes. While there is some caution in cases of advanced liver failure, most forms of hepatitis do not require protein restriction.

In summary, the use of protein as part of nutritional therapy for hepatitis is supported by scientific evidence, primarily to prevent malnutrition, promote liver regeneration, and support immune health. The strength of evidence is moderate, with recommendations endorsed by hepatology and nutrition societies.

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