Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Phellodendron, particularly the bark of Phellodendron amurense (commonly known as Amur cork tree), has been used in Traditional Chinese Medicine (TCM) for centuries. In TCM, it is called "Huang Bai" and is traditionally indicated for conditions categorized as "damp-heat," which includes various liver disorders and jaundice—symptoms often associated with hepatitis. The traditional use is primarily based on empirical observations and the herb's inclusion in classic TCM formulas, such as "Yin Chen Hao Tang," which is used for jaundice and liver inflammation.

The main active constituents, such as berberine, have demonstrated some hepatoprotective and anti-inflammatory effects in preclinical studies. However, direct clinical evidence supporting Phellodendron's use specifically for hepatitis in humans is limited. Few modern studies have been conducted in humans, and existing research is primarily in vitro or in animal models, which show potential for reducing liver enzyme levels and improving liver histology. These findings suggest a possible biological rationale, but they do not constitute strong scientific validation.

In summary, the use of Phellodendron to support or treat hepatitis is primarily justified by traditional medicine practices rather than robust scientific evidence. The evidence level is rated at 2, as there are some promising preclinical findings, but insufficient clinical data to confirm efficacy in humans.

More about Phellodendron
More about Hepatitis

Other ingredients used for Hepatitis

Other health conditions supported by Phellodendron

Products containing Phellodendron