Evidence supporting the use of: Indian Gooseberry
For the health condition: Hepatitis

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Indian Gooseberry (Phyllanthus emblica, also known as amla) has been traditionally used in Ayurveda for liver health, including conditions like hepatitis. Scientific investigations in recent years have explored its biological properties relevant to liver protection. Several preclinical studies (in vitro and animal models) demonstrate that amla possesses antioxidant, anti-inflammatory, and hepatoprotective effects. These effects are attributed largely to its high content of vitamin C, polyphenols, and tannins.

For hepatitis specifically, a handful of animal studies have shown that extracts of Indian Gooseberry can reduce liver enzyme levels and histopathological signs of liver damage induced by toxins such as carbon tetrachloride. Some studies suggest amla may help reduce oxidative stress and inhibit inflammatory cytokines involved in liver injury.

However, direct clinical evidence in humans with hepatitis is limited. Most research is preclinical, and only a few small-scale or preliminary clinical trials exist, often with methodological limitations. No large, high-quality randomized controlled trials have established its efficacy in treating hepatitis in humans.

In summary, while there is scientific rationale and some experimental evidence supporting the hepatoprotective potential of Indian Gooseberry, the quality and quantity of evidence specifically for hepatitis are modest, justifying a low-to-moderate evidence rating.

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