Evidence supporting the use of: Green chiretta
For the health condition: Hepatitis

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Green chiretta (Andrographis paniculata) has a long history of use in traditional medicine systems across Asia, particularly in Ayurveda, Traditional Chinese Medicine (TCM), and Thai herbal medicine. Traditionally, it has been used as a "liver tonic" and for the treatment of various liver disorders, including jaundice and hepatitis. The rationale for its use in hepatitis stems from its perceived "bitter" and detoxifying properties, which are thought in these systems to clear "heat" and toxins from the liver.

Some preclinical studies (in vitro and animal models) have shown that compounds in green chiretta, especially andrographolide, can exert hepatoprotective effects, reduce liver enzyme elevations, and mitigate oxidative stress in liver tissue. However, clinical evidence in humans is extremely limited and generally of low methodological quality. There are a handful of small studies and case reports suggesting possible benefits for viral hepatitis or non-specific liver dysfunction, but these are not sufficient to establish efficacy or safety for hepatitis treatment by modern medical standards.

In summary, green chiretta is traditionally used to support liver health and treat hepatitis, with some encouraging but unproven preclinical findings. Its use for hepatitis is far better supported by tradition than by rigorous clinical science, and major medical guidelines do not currently recommend it for this indication.

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