Bitter Grass, also known as Andrographis paniculata, has a longstanding use in traditional medicine systems in Asia, especially within Ayurveda and Traditional Chinese Medicine, for supporting liver health and treating ailments such as hepatitis. Traditional healers have administered extracts of Bitter Grass for symptoms associated with hepatitis, such as jaundice and liver inflammation, based on observations of its "cooling" and detoxifying properties.

Scientifically, some in vitro and animal studies have shown that Andrographis paniculata possesses hepatoprotective effects. These studies suggest antioxidant, anti-inflammatory, and potential antiviral activities of its primary bioactive compound, andrographolide. However, direct clinical evidence in humans for the treatment of hepatitis (including hepatitis B or C) remains limited and inconclusive. The majority of published work consists of preclinical research, and few if any, well-controlled human trials have established its safety and efficacy specifically for hepatitis patients.

In summary, Bitter Grass is mainly used for hepatitis due to traditional practices, with some emerging but preliminary scientific support. Its use should be approached cautiously until more rigorous clinical evidence is available.