Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Bergenia, particularly Bergenia ciliata and Bergenia ligulata, has a longstanding place in traditional medicine systems such as Ayurveda, Unani, and traditional folk medicine in South Asia. In these traditions, Bergenia is often employed for its supposed hepatoprotective (liver-protecting) effects, among other uses. Its rhizome and roots are commonly prepared in decoctions or powders to support liver health, treat jaundice, and manage various hepatic disorders, including hepatitis. This traditional use is primarily based on empirical observations and herbal lore rather than on rigorous scientific validation.

A limited number of preclinical studies (primarily in vitro and animal models) have indicated that certain phytochemicals in Bergenia, such as bergenin and arbutin, may exhibit antioxidant and anti-inflammatory activities, which could theoretically help protect liver tissue. However, direct evidence supporting the efficacy of Bergenia in treating hepatitis in humans is lacking. No high-quality clinical trials or substantial pharmacological studies have confirmed its effectiveness or safety for this indication. Therefore, while its use for hepatitis is rooted in traditional practices, the scientific evidence remains weak, with an evidence rating of 2 out of 5.

Anyone considering Bergenia for liver conditions should consult a qualified healthcare professional, as its use for hepatitis is not substantiated by robust clinical evidence.

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