Evidence supporting the use of: AHCC
For the health condition: Hepatitis

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

AHCC (Active Hexose Correlated Compound) is a standardized extract derived from the mycelia of shiitake mushrooms and is used in some settings to support liver health and immune function, including in patients with hepatitis. The rationale for its use in hepatitis, particularly chronic hepatitis C, stems from several small clinical trials and preclinical studies suggesting immunomodulatory effects. A handful of human studies, mainly from Japan, have reported that AHCC supplementation may improve liver enzyme levels (such as ALT and AST) and modulate immune responses in patients with hepatitis C. For instance, some reports indicate that AHCC can increase natural killer (NK) cell activity, which plays a role in controlling viral infections, and may reduce viral load or slow disease progression. However, these studies are generally small, not always placebo-controlled, and have methodological limitations. There is not yet robust, large-scale clinical evidence to support AHCC as an effective or standard therapy for hepatitis. Therefore, while there is preliminary scientific interest and some early clinical data, the overall quality of evidence is low, and more rigorous research is needed to confirm efficacy and safety. AHCC should not be used as a replacement for established antiviral therapies but may be considered as a complementary approach under medical supervision.

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Products containing AHCC

We currently have no products on Caring Sunshine that contain this ingredient.