Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Triterpenes are a large and diverse class of naturally occurring compounds found in many plants, including well-known medicinal herbs such as licorice (Glycyrrhiza glabra), ginseng (Panax ginseng), and milk thistle (Silybum marianum). The use of triterpene-containing plants to support the hepatic (liver) system is primarily rooted in traditional herbal medicine practices, especially in Asian and Mediterranean cultures. For example, saponin triterpenes from licorice and ginsenosides from ginseng have been used for centuries in Traditional Chinese Medicine (TCM) to promote liver health and treat liver-related ailments. However, when referencing "triterpene (unspecified)", there is no direct, robust scientific evidence validating the hepatoprotective effects of the entire class as a whole; most research focuses on specific triterpenes or triterpene-rich extracts rather than the general group. Traditional use, therefore, forms the main basis for their inclusion in liver-support formulas. The overall scientific evidence remains limited and heterogeneous, with most clinical studies involving specific compounds rather than the broad, unspecified category of triterpenes. Thus, while many triterpene-containing herbs have a long history of use for hepatic support, this use is justified more by tradition than by comprehensive modern scientific validation.

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