Evidence supporting the use of: Taxifolin
For the body system: Hepatic System

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Taxifolin, also known as dihydroquercetin, is a flavonoid found in various plants, including Siberian larch and milk thistle. Scientific studies, mostly preclinical (animal and in vitro), suggest that taxifolin has hepatoprotective properties. Its mechanisms appear to involve antioxidant, anti-inflammatory, and anti-fibrotic effects. For example, research published in Biochimica et Biophysica Acta (2014) demonstrated that taxifolin attenuates oxidative stress and liver injury in animal models. Another study in Phytotherapy Research (2020) reported that taxifolin reduced markers of liver fibrosis and inflammation in rats exposed to hepatotoxins. In these studies, taxifolin improved liver enzyme profiles and histological features of the liver.

However, there is a lack of robust clinical trials in humans to confirm these effects. While the biochemical rationale and preclinical data are promising, evidence in human populations is limited or absent. Taxifolin is not a standard therapy for liver diseases, but it is included in some dietary supplements marketed for liver health based on its antioxidant profile. Thus, the use of taxifolin for hepatic support is primarily supported by scientific rationale and preclinical evidence, but not yet by high-quality clinical studies.

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Other ingredients that support Hepatic System

amino acids
artichoke
barberry
berberine
black garlic
bovine
bovine liver
broccoli
bupleurum falcatum
turmeric
curcumin
d-glucarate
dandelion
epigallocatechin gallate (EGCG)
fructose
garlic bulb
gentian root
gooseberry
green tea
hesperetin
kale
l-glutathione
l-methionine
l-ornithine
lecithin
liquid liver fractions
matcha
milk thistle
n-acetyl-cysteine (NAC)
naringin
niacin (vitamin B3)
niacinamide (vitamin B3)
nicotinamide riboside
oleanolic acid
olive
ox bile
pantethine
parsley
phenolic acids
phosphatidylcholine
phospholipids
pumpkin
riboflavin (vitamin B2)
silymarin
sulforaphane glucosinolate
tocotrienols
trimethylglycine (TMG)
triphala
vitamin B
water
watercress
zinc
jiaogulan
punarnava
picrorhiza kurroa
lingzhi
bile salt
ferulic acid
ganoderma
polyphenols
trace minerals
herbal blend (proprietary)
algae
AMP-activated protein kinase (AMPK)
Apigenin
Antrodia camphorata
Arginine carglumate
AHCC
Andrographolide
Alpha-Lipoic Acid
Ampelopsin
Animal protein
Black Seed
Borotutu
Brassica
Beef liver
Baicalein
Basidiomycota
boldo
Betanin
berry
Bitter principals
bile acid
Bupleurum
Boerhavia diffusa
cholic acid
Carqueja
Catalpol
Coenzyme A
Capillary Artemisia
chlorogenic acid
Curcuminoid
Cynarin
Cruciferous
Capers
Chanca Piedra
Curcuma
Chinese Thoroughwax
Corilagin
Cynaropicrin
Dihydromyricetin
DL-Methionine
Dehydrocholic acid
Dihydrolipoic Acid
Dithiolthiones
Eriocitrin
Egg
Eclipta
Emblicanin
Fringetree
Flavonolignan
Ginsenosides
Gamma-Glutamylcysteine
Gallate
glucose
Glycocholic acid
Glycyrrhetinic Acid
Guggulsterones
Glycyrrhizin
Gentiana manshurica
Glycochenodeoxycholic acid

Products containing Taxifolin

We currently have no products on Caring Sunshine that contain this ingredient.