Evidence supporting the use of: Sulforaphane glucosinolate
For the body system: Hepatic System
Synopsis
Source of validity: Scientific
Rating (out of 5): 4
Sulforaphane glucosinolate, commonly found in cruciferous vegetables such as broccoli, is a precursor to sulforaphane, a well-studied isothiocyanate. Scientific evidence supports its use in supporting the hepatic (liver) system primarily through its ability to induce phase II detoxification enzymes, such as glutathione S-transferase and quinone reductase, which are crucial for the detoxification of harmful compounds. Multiple preclinical studies and several human clinical trials have demonstrated that sulforaphane increases the activity of these enzymes in the liver, enhancing the organ’s ability to process and eliminate toxins. For example, a study published in Cancer Epidemiology, Biomarkers & Prevention (2007) showed that broccoli sprout beverages rich in sulforaphane increased the excretion of airborne carcinogens in humans, indicating activation of liver detoxification pathways. Additionally, sulforaphane has shown hepatoprotective effects in animal models, protecting liver tissue from chemical-induced damage and reducing markers of oxidative stress and inflammation. While there is a strong mechanistic basis and supportive human data, more large-scale clinical trials are needed to fully establish its efficacy in specific hepatic conditions. Nonetheless, the scientific foundation for using sulforaphane glucosinolate to support liver health and detoxification processes is considered robust.
More about sulforaphane glucosinolate
More about Hepatic System
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amino acidsartichoke
barberry
berberine
black garlic
bovine
bovine liver
broccoli
bupleurum falcatum
turmeric
curcumin
d-glucarate
dandelion
epigallocatechin gallate (EGCG)
fructose
garlic bulb
gentian root
gooseberry
green tea
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l-glutathione
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l-ornithine
lecithin
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naringin
niacin (vitamin B3)
niacinamide (vitamin B3)
nicotinamide riboside
oleanolic acid
olive
ox bile
pantethine
parsley
phenolic acids
phosphatidylcholine
phospholipids
pumpkin
riboflavin (vitamin B2)
silymarin
sulforaphane glucosinolate
tocotrienols
trimethylglycine (TMG)
triphala
vitamin B
water
watercress
zinc
jiaogulan
punarnava
picrorhiza kurroa
lingzhi
bile salt
ferulic acid
ganoderma
polyphenols
trace minerals
herbal blend (proprietary)
algae
AMP-activated protein kinase (AMPK)
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Antrodia camphorata
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AHCC
Andrographolide
Alpha-Lipoic Acid
Ampelopsin
Animal protein
Black Seed
Borotutu
Brassica
Beef liver
Baicalein
Basidiomycota
boldo
Betanin
berry
Bitter principals
bile acid
Bupleurum
Boerhavia diffusa
cholic acid
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Coenzyme A
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chlorogenic acid
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Cruciferous
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Chanca Piedra
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Other body systems supported by sulforaphane glucosinolate
BrainCirculatory System
Digestive System
Gastrointestinal Tract
Heart
Hepatic System
Immune System
Intestinal System
Large Intestines (Colon)
Liver
Lungs
Mitochondria
Respiratory System
Skin
Small Intestines