Evidence supporting the use of: Phyllanthus (unspecified)
For the body system: Hepatic System

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Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Phyllanthus is a genus of plants that includes several species commonly used in traditional medicine, notably Phyllanthus niruri, also known as "Chanca Piedra" or "stonebreaker." The use of Phyllanthus species to support the hepatic (liver) system is supported by both traditional practices and scientific research. Traditionally, Phyllanthus has been used in Ayurveda and other systems of medicine for its purported liver-protective properties, particularly in managing jaundice and other liver disorders.

Scientifically, several studies have investigated the hepatoprotective effects of Phyllanthus extracts, especially P. niruri. In vitro and animal studies suggest that Phyllanthus has antioxidant, anti-inflammatory, and antiviral effects, which may help protect liver cells from damage. Some clinical trials, mainly small and preliminary, have evaluated Phyllanthus in the context of viral hepatitis B, with a few studies showing reduced viral load and improvement in liver function markers. However, results are mixed and more robust, large-scale human studies are needed to confirm these effects and establish clear therapeutic recommendations.

Overall, while there is a moderate degree of scientific validation for the use of Phyllanthus in supporting liver health, particularly in terms of hepatoprotective and antiviral properties, the evidence is not yet strong enough for definitive clinical recommendations. Its safety profile appears favorable in the short term, but long-term effects have not been well studied.

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