Synopsis

Source of validity: Scientific
Rating (out of 5): 4

Phospholipids, particularly phosphatidylcholine (PC), have scientific evidence supporting their use in supporting hepatic (liver) function. Phospholipids are a major component of cell membranes, including hepatocytes (liver cells), and are involved in membrane fluidity, signaling, and lipid transport. Several clinical and preclinical studies have investigated the hepatoprotective effects of phospholipids, especially in the context of liver diseases such as non-alcoholic fatty liver disease (NAFLD), alcoholic liver disease, and drug-induced liver injury.

Phosphatidylcholine, often derived from soy or egg, has been shown to improve liver enzyme profiles, reduce liver fat accumulation, and support liver regeneration in various studies. The mechanism is thought to involve stabilization of cell membranes, enhancement of lipid metabolism, and anti-inflammatory effects. For example, a review published in World Journal of Gastroenterology (2014) summarized clinical trials where administration of essential phospholipids led to improvements in liver function tests and histological findings in patients with chronic liver diseases.

While not all studies are universally positive and some methodological limitations exist, the accumulated evidence—both experimental and clinical—supports the use of phospholipids, particularly phosphatidylcholine, in the support of hepatic health. The use is not based merely on tradition, but is underpinned by a reasonable body of scientific research, though further high-quality studies are warranted to clarify their role in specific liver conditions.

More about Phospholipids (unspecified)
More about Hepatic System

Other ingredients that support Hepatic System

Other body systems supported by Phospholipids (unspecified)

Products containing Phospholipids (unspecified)