Synopsis

Source of validity: Scientific
Rating (out of 5): 5

Glucose plays a critical role in supporting the hepatic (liver) system, with extensive scientific validation for its use. The liver is central to glucose metabolism, being responsible for glycogen storage and gluconeogenesis (the production of glucose from non-carbohydrate sources). Medical practice routinely uses glucose administration in cases of hypoglycemia, liver disease, and during parenteral nutrition, especially when liver function is compromised or energy demands are high.

In acute liver failure or hepatic insufficiency, glucose is often infused to prevent hypoglycemia, a common and life-threatening complication due to impaired gluconeogenesis and glycogenolysis. Guidelines from major hepatology and critical care societies recommend intravenous glucose for patients at risk. Furthermore, in the perioperative management of patients with liver disease or undergoing hepatic surgery, glucose-containing solutions are employed to maintain normoglycemia and support metabolic requirements.

Numerous clinical studies and reviews (e.g., in journals such as Hepatology and The Lancet) document the pivotal role of glucose in preventing metabolic decompensation and supporting hepatic recovery. The administration of glucose is not just a tradition, but a scientifically validated practice grounded in the understanding of hepatic physiology and metabolic needs. Thus, the use of glucose to support the hepatic system is well-established and rated at the highest level of scientific evidence.

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