Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Various fungi, particularly medicinal mushrooms such as Reishi (Ganoderma lucidum), Shiitake (Lentinula edodes), and Turkey Tail (Trametes versicolor), have long been used in traditional medicine systems, especially in East Asia, to support liver health and the hepatic system. In Traditional Chinese Medicine (TCM), these mushrooms are believed to "nourish the liver," promote detoxification, and support overall vitality. Historical texts and ethnobotanical records describe their use in treating symptoms associated with liver dysfunction, such as jaundice and hepatitis, although these were based on observational and experiential practices rather than controlled studies.

Modern scientific research on specific fungi shows some preliminary evidence for hepatoprotective effects, mainly in cell and animal studies. Compounds found in mushrooms, such as polysaccharides and triterpenoids, have demonstrated antioxidant and anti-inflammatory properties that may protect liver cells from damage. However, robust clinical trials in humans are limited, and most evidence supporting fungal use for hepatic health is derived from traditional use rather than rigorous scientific validation. Thus, while there is a long-standing tradition of using fungi to support the hepatic system, the current level of scientific evidence is modest, warranting further research.

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