Synopsis

Source of validity: Scientific
Rating (out of 5): 3

Flavones are a class of polyphenolic compounds found in various plants, including parsley, celery, and chamomile. They are well-studied for their antioxidant, anti-inflammatory, and hepatoprotective properties. Scientific research, primarily in vitro and in animal models, suggests that flavones such as apigenin and luteolin can protect liver cells from oxidative stress and inflammation. These compounds have been shown to modulate the activity of enzymes involved in detoxification and may reduce liver fibrosis by inhibiting the activation of hepatic stellate cells. Some studies indicate that flavones can decrease markers of liver injury, such as aminotransferases, and improve histological signs of liver health in models of chemically-induced liver damage. However, while preclinical studies are promising, there is limited direct clinical evidence in humans supporting the use of flavones for liver protection or the treatment of hepatic diseases. Most human research involves dietary intake of flavone-rich foods and their general association with better liver markers, rather than isolated flavone supplementation. Therefore, while the mechanistic basis and traditional use for liver support exist, and animal studies are supportive, the overall evidence for effectiveness in humans is moderate and requires more robust clinical trials.

More about Flavones (various)
More about Hepatic System

Other ingredients that support Hepatic System

Other body systems supported by Flavones (various)

Products containing Flavones (various)