Synopsis

Source of validity: Traditional
Rating (out of 5): 3

Basidiomycota, a large phylum of fungi that includes mushrooms like Reishi (Ganoderma lucidum), Turkey Tail (Trametes versicolor), and Shiitake (Lentinula edodes), has been traditionally used in various cultures to support liver (hepatic) health. Traditional Chinese Medicine (TCM) and Japanese Kampo have long utilized these mushrooms for their perceived detoxifying, hepatoprotective, and immune-modulating properties. For instance, Reishi is often referred to as the "mushroom of immortality" and has a long history of use for promoting longevity and liver health.

Scientific research has begun to explore these traditional uses, with several in vitro and animal studies suggesting that certain Basidiomycota species possess hepatoprotective effects, likely due to their polysaccharides, triterpenoids, and antioxidant compounds. Some studies have demonstrated reduced markers of liver damage and improved liver function in animal models given extracts from these mushrooms. However, robust clinical trials in humans are limited, and the evidence remains largely preliminary. Thus, the primary support for using Basidiomycota to benefit the hepatic system is rooted in tradition, with some emerging but not yet conclusive scientific backing.

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