Evidence supporting the use of: Troxerutin
For the health condition: Hemorrhoids

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Troxerutin is a flavonoid derivative (a type of rutin) that has been used in the management of chronic venous insufficiency and related vascular disorders, including hemorrhoids. The rationale for its use is primarily based on its vasoprotective, anti-inflammatory, and antioxidant properties. Several clinical studies, mostly conducted in Europe and Asia, have evaluated the efficacy of troxerutin in relieving symptoms associated with hemorrhoids, such as pain, bleeding, and swelling. These studies generally suggest that troxerutin may help reduce capillary permeability, strengthen blood vessel walls, and decrease edema, which are relevant mechanisms in the treatment of hemorrhoidal disease. However, the overall quality of evidence is limited. Most studies are small, short-term, and of moderate methodological quality. There are few large, high-quality randomized controlled trials directly comparing troxerutin to placebo or to other standard treatments for hemorrhoids. Some international guidelines acknowledge the use of flavonoids (including troxerutin) as an adjunctive therapy in the symptomatic treatment of hemorrhoids, but they also note the need for more robust evidence. In summary, while there is some scientific basis and clinical experience supporting the use of troxerutin for hemorrhoids, the strength of the evidence is moderate at best. It may offer symptom relief for some patients, but it should not be considered a standalone or primary therapy in the absence of stronger supporting data.

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Products containing Troxerutin

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