Evidence supporting the use of: Rutin
For the health condition: Hemorrhoids

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Rutin is a flavonoid found in various plants such as buckwheat, apples, and citrus fruits, and has a long history of use for vascular health. Its use in supporting or treating hemorrhoids is primarily justified by scientific research, although the strength of evidence is moderate rather than robust. Rutin is believed to strengthen capillaries, reduce capillary permeability, and exhibit anti-inflammatory and antioxidant properties, which are relevant to the pathophysiology of hemorrhoids—enlarged, inflamed veins in the rectal area.

Several clinical trials and observational studies have investigated the benefits of flavonoids, including rutin, for hemorrhoids. Most notably, micronized purified flavonoid fraction (MPFF), which contains diosmin and hesperidin (related compounds), has demonstrated efficacy in reducing hemorrhoidal symptoms such as bleeding, pain, and itching. Some studies specifically using rutin, often in combination with vitamin C, suggest improvements in capillary fragility and reduction in symptoms of chronic venous insufficiency, which is mechanistically related to hemorrhoidal disease.

However, the direct evidence for rutin alone in the treatment of hemorrhoids is limited, and many studies use it as part of a complex or combination product. The European Medicines Agency recognizes the traditional use of rutin-containing preparations for minor venous circulatory disturbances, which can include hemorrhoids. Overall, while there is some scientific basis for rutin's use in this context, further high-quality, targeted clinical trials are needed to confirm its efficacy.

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Other ingredients used for Hemorrhoids

Abrus
Acacia
Achyranthes
Aconite
Aerva lanata
Aescin
Agrimonia pilosa
Agrimony
Ajuga
Alchemilla
Allicin
Allium tuberosum
Aloe vera
American Liverleaf
Amor seco
Angelica
anthocyanidins
anthraquinone
Antirrhinum majus
antler
apple
apple cider vinegar
apricot
Ardisia
aster root
avens
bael
Baliospermum
banyan
Barleria
Bassia scoparia
bayleaf
Bergenia
betel
bilberry
bioflavonoids
birch
Black Hellebore
black nightshade
black root
blackberry
blackboard tree
Blepharis
Borassus aethiopum
borassus palm
bran
Brassica
butcher's broom
cabbage
cactus
Caesalpinia crista
capsicum
Carthamus
castor oil
Celosia
chamomile
chard
chestnut
Chinese silkvine
Chondrus
cinquefoil
citrus bioflavonoids
Clerodendrum indicum
coconut oil
colocynth
commiphora
Cucurbita
Cyathula
Cynodon dactylon
dandelion
Dianthus
Diosmin
elephant\'s head
Embelia
escin
fiber
fiber blend (proprietary)
Ficus simplicissima
geranium
gotu kola
green chiretta
hazelnut
horse chestnut
Indian coraltree
Kokilaksha
labrador tea
lemon
lichen
licorice root
little ironweed
Lycopodium
Methylcellulose
Mezoneuron benthamianum
Morinda
Morning glory
Morus
Mountain Pepper
Mucilage
Myrrh
Nettle
Nimbidin
Nymphaea nouchali
Oak
Oligomeric proanthocyanidins
Onosma bracteatum
oregon grape
Oroxylum indicum
pagoda tree
Papayotin
parsley
paw paw
Pentacyclic triterpenoids
peony
Persimmon
phellodendron amurense
Pluchea
plum fruit
Polygonum
Portulaca
proanthocyanidins
prune
Prunus
psyllium
punarnava
rhubarb
Rosa laevigata
Rosabin
Rubia cordifolia
Ruscogenins
Ruscus
rutin
Rutosides
Sanguisorba
Sarivan
sea salt
seaweed
Shark Liver Oil
shepherd's purse
slippery elm bark
Sumac
Sword Bean
Szechuan lovage
Tamarind
Tannins
Taraxacin
Terminalia
Triphala
Troxerutin
turmeric
Varuna
vitamin C
Wax Gourd
Winter Begonia
Witch Hazel
Yellow Dock
Zinc
Zucchini