Evidence supporting the use of: Proanthocyanidins (unspecified)
For the health condition: Hemorrhoids
Synopsis
Source of validity: Traditional
Rating (out of 5): 2
Proanthocyanidins, particularly those derived from grape seed extract and certain plants, have a history of use in traditional and alternative medicine for vascular health, including the management of hemorrhoids. The rationale for their use is based on their purported ability to strengthen blood vessel walls, reduce capillary fragility, and improve venous tone, all of which are relevant to the pathophysiology of hemorrhoids. Traditional European herbal medicine has employed extracts rich in proanthocyanidins for the treatment of chronic venous insufficiency and related symptoms such as varicose veins and hemorrhoids. However, scientific validation for their efficacy specifically in hemorrhoids is limited. Some small-scale clinical studies and observational data suggest a benefit in reducing symptoms like bleeding, pain, and swelling, but these are often not of high methodological quality or are extrapolated from studies on chronic venous insufficiency rather than hemorrhoids directly. Furthermore, most studies focus on micronized purified flavonoid fractions (MPFF) or specific formulations, rather than unspecified proanthocyanidins. Systematic reviews and clinical guidelines do not robustly support their use due to the paucity of high-quality evidence. In summary, the use of proanthocyanidins for hemorrhoids is primarily rooted in traditional practice and extrapolated vascular benefits, with limited and indirect scientific support. More rigorous clinical trials are needed to establish their efficacy for this indication.
More about Proanthocyanidins (unspecified)
More about Hemorrhoids
Other ingredients used for Hemorrhoids
Aloe veragreen chiretta
apple
apricot
berry flavor
betel
bilberry
blackberry
butcher's broom
chamomile
citrus bioflavonoids
turmeric
dandelion
fiber blend (proprietary)
gotu kola
cellulose
horse chestnut
lemon
licorice root
nettle
oregon grape
parsley
phellodendron amurense
plum fruit
prune
psyllium
rutin
slippery elm bark
triphala
vitamin C
seaweed
zinc
tangerine
capsicum
punarnava
commiphora
blackboard tree
caesalpinia crista
rubia cordifolia
peony
Szechuan lovage
morus
myrrh
morinda
birch
aster root
shepherd's purse
paw paw
geranium
sea salt
Avens
Apple Cider Vinegar
Antler
Anthraquinone
Ardisia
Angelica
Acacia
Agrimony
Allicin
Antirrhinum majus
Achyranthes
Abrus
Alchemilla
Aconite
Ajuga
Aerva lanata
American Liverleaf
Aescin
anthocyanidins
Agrimonia pilosa
Allium tuberosum
Amor seco
Baliospermum
Blepharis
Brassica
Bayleaf
Bran
Barleria
Bael
Banyan
Bioflavonoids
Black Nightshade
Borassus Palm
Borassus aethiopum
Black root
Bassia scoparia
Black Hellebore
Bergenia
Chinese Silkvine
Cucurbita
coconut oil
Cactus
Cinquefoil
Cyathula
Chard
Cabbage
Chestnut
Cynodon dactylon
Castor Oil
Carthamus
Colocynth
Celosia
Clerodendrum indicum
Chondrus
Dianthus
Diosmin
Elephant's Head
Escin
Embelia
Fiber
Ficus simplicissima
Hazelnut
Indian Coraltree
Kokilaksha
Lichen
Lycopodium
Labrador Tea
Little ironweed
methylcellulose
Mezoneuron benthamianum
Mountain Pepper
Mucilage
Morning Glory
Nymphaea nouchali
Nimbidin
Oak
Oroxylum indicum
Oligomeric proanthocyanidins
Onosma bracteatum
Pagoda Tree
Pluchea
Potato
Prunus
Pentacyclic triterpenoids
Proanthocyanidins
portulaca
Persimmon
Papayotin
Polygonum
Rosabin
Ruscus
Ruscogenins
Rosa laevigata
Rutosides
Rhubarb
Shark Liver Oil
Sanguisorba
Sarivan
Squash
Sumac
Sword Bean
Terminalia
Tannins
Taraxacin
Troxerutin
Tamarind
Varuna
Wax Gourd
Witch Hazel
Winter Begonia
Yellow Dock
Zucchini
Other health conditions supported by Proanthocyanidins (unspecified)
Bruises (healing)Cancer (natural therapy for)
Cancer (prevention)
Cardiovascular Disease
Cholesterol (high)
Circulation (poor)
Colitis
Diabetes
Diabetic Retinopathy
Edema
Free Radical Damage
Gastritis
Gingivitis
Hemorrhoids
Hypertension
Inflammation