Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Polyphenols are a group of naturally occurring compounds found in plants, known for their antioxidant and anti-inflammatory properties. Their use in supporting or treating hemorrhoids is primarily rooted in traditional medicine, particularly in the use of polyphenol-rich plant extracts such as witch hazel (Hamamelis virginiana), horse chestnut (Aesculus hippocastanum), and grape seed extract. These substances have historically been applied topically or taken orally to reduce the swelling, pain, and discomfort associated with hemorrhoids. The rationale is that their anti-inflammatory effects may help decrease local inflammation and strengthen blood vessel walls, thus alleviating hemorrhoidal symptoms.

Scientific evidence for the effectiveness of polyphenols (mixed or specific) in treating hemorrhoids is limited, with most available studies being small, poorly controlled, or focused on specific extracts rather than mixed polyphenols as a category. Some clinical trials suggest that horse chestnut seed extract and flavonoids (a type of polyphenol) may reduce symptoms of chronic venous insufficiency and hemorrhoids, but these findings are not robust enough to warrant strong scientific endorsement. Systematic reviews often call for more rigorous research. As such, while traditional use is widespread, scientific validation is modest, leading to a low-to-moderate evidence rating.

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