Evidence supporting the use of: Nimbidin
For the health condition: Hemorrhoids

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Nimbidin is a bitter compound isolated from the seeds of the neem tree (Azadirachta indica). Its use in supporting or treating hemorrhoids is rooted primarily in traditional Ayurvedic and folk medicine practices, especially in India. Historically, neem and its derivatives, including nimbidin, have been used topically and orally for their anti-inflammatory, antimicrobial, and wound-healing properties. These properties are considered beneficial in managing the symptoms of hemorrhoids, such as inflammation, pain, and infection risk. However, direct clinical studies evaluating nimbidin's efficacy in hemorrhoid treatment are lacking.

Most available evidence consists of in vitro studies and animal models demonstrating nimbidin’s anti-inflammatory and analgesic effects. For example, research has shown nimbidin can inhibit prostaglandin synthesis and modulate immune responses, supporting its traditional use for inflammation-related conditions. However, these effects have not been specifically validated in the context of human hemorrhoidal disease. No large-scale randomized controlled trials or meta-analyses substantiate its effectiveness for hemorrhoids in humans.

In summary, nimbidin’s use for hemorrhoids is mainly based on traditional knowledge and preliminary laboratory studies rather than robust clinical evidence. Thus, while there is a rationale for its use rooted in its known pharmacological actions, high-quality scientific validation for this specific indication is lacking.

More about Nimbidin
More about Hemorrhoids

Other ingredients used for Hemorrhoids

Aloe vera
green chiretta
apple
apricot
berry flavor
betel
bilberry
blackberry
butcher's broom
chamomile
citrus bioflavonoids
turmeric
dandelion
fiber blend (proprietary)
gotu kola
cellulose
horse chestnut
lemon
licorice root
Nettle
oregon grape
parsley
phellodendron amurense
plum fruit
prune
psyllium
rutin
slippery elm bark
Triphala
vitamin C
seaweed
Zinc
tangerine
capsicum
punarnava
commiphora
blackboard tree
Caesalpinia crista
Rubia cordifolia
peony
Szechuan lovage
Morus
Myrrh
Morinda
birch
aster root
shepherd's purse
paw paw
geranium
sea salt
avens
apple cider vinegar
antler
anthraquinone
Ardisia
Angelica
Acacia
Agrimony
Allicin
Antirrhinum majus
Achyranthes
Abrus
Alchemilla
Aconite
Ajuga
Aerva lanata
American Liverleaf
Aescin
anthocyanidins
Agrimonia pilosa
Allium tuberosum
Amor seco
Baliospermum
Blepharis
Brassica
bayleaf
bran
Barleria
bael
banyan
bioflavonoids
black nightshade
borassus palm
Borassus aethiopum
black root
Bassia scoparia
Black Hellebore
Bergenia
Chinese silkvine
Cucurbita
coconut oil
cactus
cinquefoil
Cyathula
chard
cabbage
chestnut
Cynodon dactylon
castor oil
Carthamus
colocynth
Celosia
Clerodendrum indicum
Chondrus
Dianthus
Diosmin
elephant\'s head
escin
Embelia
fiber
Ficus simplicissima
hazelnut
Indian coraltree
Kokilaksha
lichen
Lycopodium
labrador tea
little ironweed
Methylcellulose
Mezoneuron benthamianum
Mountain Pepper
Mucilage
Morning glory
Nymphaea nouchali
Nimbidin
Oak
Oroxylum indicum
Oligomeric proanthocyanidins
Onosma bracteatum
pagoda tree
Pluchea
potato
Prunus
Pentacyclic triterpenoids
proanthocyanidins
Portulaca
Persimmon
Papayotin
Polygonum
Rosabin
Ruscus
Ruscogenins
Rosa laevigata
Rutosides
rhubarb
Shark Liver Oil
Sanguisorba
Sarivan
Squash
Sumac
Sword Bean
Terminalia
Tannins
Taraxacin
Troxerutin
Tamarind
Varuna
Wax Gourd
Witch Hazel
Winter Begonia
Yellow Dock
Zucchini

Products containing Nimbidin

We currently have no products on Caring Sunshine that contain this ingredient.