Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Enzymes, particularly proteolytic enzymes such as bromelain, trypsin, and chymotrypsin, have traditionally been used in some cultures and alternative medicine systems to support the treatment of hemorrhoids. The rationale is that these enzymes may help reduce inflammation, edema, and promote healing by breaking down inflammatory mediators and fibrin. Historical use is most notable in naturopathic and herbal medicine contexts, especially in Europe and India, where enzyme preparations have been included in oral or topical remedies for hemorrhoids. However, scientific validation of these claims is limited. A few small clinical studies and case reports suggest that proteolytic enzymes might reduce swelling and discomfort in hemorrhoidal disease, but these studies are often methodologically weak, have small sample sizes, or lack rigorous controls. Systematic reviews and major clinical guidelines do not endorse enzymes as a primary therapy for hemorrhoids due to insufficient evidence. Most conventional medical approaches favor fiber supplementation, topical treatments, and procedural interventions. As such, the use of unspecified enzymes for hemorrhoids is primarily supported by tradition and anecdotal experience rather than robust scientific research.

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Other ingredients used for Hemorrhoids

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