Evidence supporting the use of: Chlorella
For the health condition: Heavy Metal Poisoning

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Synopsis

Source of validity: Scientific
Rating (out of 5): 2

Chlorella, a type of freshwater green algae, is often promoted as a supplement to support detoxification, particularly regarding heavy metal poisoning. The rationale for its use stems from chlorella's cell wall composition, which is rich in polysaccharides and thought to bind heavy metals such as mercury, cadmium, and lead, thereby facilitating their excretion from the body. Several small animal studies have demonstrated that chlorella supplementation can reduce the absorption and enhance the elimination of heavy metals. For example, rodent studies have reported lower tissue concentrations of mercury and cadmium following chlorella administration. There are also a few small human studies and case reports suggesting potential benefits; for instance, some research has shown a reduction in certain blood or urinary heavy metal levels in people using chlorella supplements. However, the overall quality and quantity of clinical evidence are limited. Most human studies are small, lack rigorous controls, or use chlorella in combination with other agents, making it difficult to attribute effects to chlorella alone. Systematic reviews highlight the need for larger, well-designed clinical trials to establish efficacy and safety. While the mechanistic rationale is plausible and animal data are supportive, the evidence in humans remains preliminary. Therefore, chlorella’s use for heavy metal detoxification is best described as having limited scientific support at this time.

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