Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Mulberry, particularly the leaves and fruit of Morus alba and related species, has a longstanding place in traditional medicine systems such as Traditional Chinese Medicine (TCM) and Ayurveda. In TCM, mulberry is considered beneficial for nourishing the blood, tonifying the heart, and alleviating symptoms associated with "heart weakness," which may refer to general fatigue, palpitations, or poor circulation rather than specific cardiac pathologies. Mulberry fruit (Sang Shen) is used to support the heart and liver, believed to enrich the yin and promote fluid production, which indirectly supports heart function. However, these concepts do not correspond directly to Western biomedical definitions of heart disease or heart failure.

Scientific research on mulberry's cardiovascular effects is limited and primarily focuses on its antioxidant, antihyperglycemic, and lipid-lowering properties. Some animal and in vitro studies suggest mulberry extracts may reduce oxidative stress, improve lipid profiles, and lower blood pressure, which could theoretically benefit cardiovascular health. However, robust clinical trials specifically evaluating mulberry for "heart weakness" or heart failure in humans are lacking. Thus, while the traditional use is well documented, scientific validation remains preliminary. The overall evidence supporting mulberry for this condition is limited to traditional use with some supportive, but not definitive, preclinical data.

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