Evidence supporting the use of: Knotweed (unspecified)
For the health condition: Heart (weakness)

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Synopsis

Source of validity: Traditional
Rating (out of 5): 2

Various species of knotweed, most notably Polygonum multiflorum (known as He Shou Wu or Fo-Ti in traditional Chinese medicine), have a long history of use in traditional herbal systems for supporting heart health and treating what is sometimes described as "heart weakness." In traditional Chinese medicine (TCM), He Shou Wu is believed to tonify the blood, strengthen the heart, and promote longevity. These uses are primarily based on centuries-old texts and anecdotal reports rather than rigorous scientific evidence.

Scientific investigations into knotweed's effects on cardiovascular health are limited and inconclusive. While some laboratory studies have suggested antioxidant and vasodilatory effects from extracts of Polygonum multiflorum, direct evidence supporting its efficacy for heart weakness or heart failure in humans is lacking. Furthermore, concerns have been raised regarding potential hepatotoxicity with long-term use of P. multiflorum.

Other knotweed species, such as Japanese knotweed (Polygonum cuspidatum), are known for their resveratrol content, which has been studied for cardiovascular benefits. However, the use of Japanese knotweed specifically for "heart weakness" is not well documented in historical or scientific literature. Overall, the use of knotweed for supporting the heart is justified mainly by traditional practices, with limited scientific validation.

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